If you’ve been playing Fallout 76 for a while and reached the endgame content, you know how important it is to have the right arsenal at your disposal. Whether you’re gearing up for high-level PvE challenges or competitive PvP encounters, having powerful weapons can make all the difference. After countless hours of testing and theorycrafting, I’ve put together a list of the 16 most powerful weapons to carry into the late game.

Before diving in, a quick tip for those who might need to top off their supplies or want to buy Fallout 76 items cheap: there are several reliable sources where you can purchase weapons, ammo, or caps, including options to buy Fallout 76 Caps cheap if you’re low on funds. This can help you focus on upgrading your build rather than grinding endlessly.

Now, let’s break down these weapons by their effectiveness, versatility, and ease of acquisition:

  1. Gauss Rifle
    A favorite for many, the Gauss Rifle packs a serious punch with high damage per shot and excellent range. It’s fantastic for taking down tough enemies and is even better when modded for accuracy and damage.

  2. The Overseer’s Guardian
    This unique legendary combat rifle shoots two projectiles per shot, effectively doubling its damage output. It’s incredibly versatile for both PvP and PvE.

  3. Dragon
    One of the most sought-after endgame weapons, the Dragon has a chance to stagger opponents with each shot, making it a nightmare for foes. It’s a high-damage lever-action rifle perfect for sharpshooters.

  4. Deliverer
    For players who love stealth and VATS, the Deliverer is unmatched. Its high AP regeneration and accuracy make it a go-to sidearm for sneaky builds.

  5. Bloodied Two-Shot Explosive Combat Rifle
    Combining the bloodied build’s bonus damage with explosive rounds, this rifle can obliterate groups of enemies quickly. It’s a bit resource-heavy but worth the investment.

  6. Shishkebab
    Though melee weapons aren’t always the first choice, the Shishkebab’s fire damage and unique animation make it a fun and effective close-range weapon.

  7. Bolt-Action Rifle
    Simple but deadly, this rifle scales well with a sniper build and can be found relatively early. Mod it for max damage, and it becomes a reliable long-range weapon.

  8. Nail Gun
    This underrated weapon benefits from high critical damage and excellent bleed effects, making it a surprising contender in endgame fights.

  9. The Fixer
    With a fast fire rate and decent damage, The Fixer shines in mid-range combat. Its legendary effect to repair itself makes it very durable for extended battles.

  10. Gatling Laser
    For those who prefer energy weapons, the Gatling Laser’s sustained fire can mow down enemies with ease, especially with a maxed-out Strength build.

  11. MIRV
    This missile launcher can clear entire groups at once with its multiple warheads. It’s perfect for crowd control but requires careful ammo management.

  12. Handmade Rifle
    Highly customizable and with good accuracy, the Handmade Rifle fits many build styles and is excellent for consistent damage output.

  13. Grognak’s Axe
    A powerful melee weapon that complements strength builds, it delivers high damage with each swing and comes with a nice crit boost.

  14. Bloodied Spray and Pray
    If you enjoy using SMGs, this weapon’s increased critical hit chance synergizes well with a bloodied build, turning it into a rapid-fire death machine.

  15. Kellogg’s Pistol
    A solid sidearm with good range and damage, Kellogg’s Pistol can be found relatively easily and modded into a reliable backup weapon.

  16. Flamer
    While situational, the Flamer is devastating against groups of weaker enemies and can keep them locked down with persistent fire damage.

Having access to these weapons makes tackling the toughest parts of Appalachia much more manageable. If you’re ever in need of resources or want to upgrade quickly, don’t hesitate to look for ways to buy Fallout 76 items cheap or to Buy Fallout 76 Caps cheap, as having ample caps can speed up crafting and trading. I’ve personally used platforms like U4GM in the past to ease the grind, though always with caution and good research.

Remember, the best weapon for you might depend on your build, playstyle, and the enemies you face most often. Experiment with these choices and mod them to fit your needs.