It's been six years since the won the AFC South, but expectations are much different in 2020 with coach Frank Reich and Co. finally embracing a big-name replacement for under center. After 16 years quarterbacking the , is now Indy's gunslinger, giving the Colts hope for a return to Jose Reyes Jersey playoff contention. The journey toward a potential postseason berth begins right inside the division on Sunday, with the rival playing host to their 2020 kickoff.Is there any way the rebuilding Jags can pull off a Week 1 upset? How, exactly, will Rivers look in his Asdrubal Cabrera Jersey first gig with the Colts? We'll find out this Sunday afternoon. Here's everything you need to know about catching the AFC South battle:How to watchDate:Sunday, Sept. 13 |Time:1 p.m. ETLocation:TIAA Bank Field (Jacksonville, Florida)TV:CBS|Stream: Follow:Prediction had the benefit of a full -- if pandemic-affected -- offseason as Jacksonville's starting quarterback, and his chemistry with D.J. Chark could pose a few i sues for a transitioning Colts secondary featuring castoff . But let's not kid ourselves: The Jags don't have much else going for them here.Exiling young talents like , and over the last year or so, Jacksonville is seriously bereft of depth Jed Lowrie Jersey acro s the board. Outside of Chark and rookie Laviska Shenault, Minshew might be forced to check down to running back behind a shaky offensive line. And the defense isn't much better, unle s Amed Rosario Jersey rookies like and C.J. Henderson make unprecedented early impacts.The Colts, meanwhile, are sure to run into some hurdles of their own with Rivers debuting with an entirely new supporting cast. The thing is, that supporting cast is good. Behind one of the NFL's sturdiest O-lines, the ex-Chargers QB should have plenty of time to find play-makers like T.Y. Hilton and rookie Jr. -- and then lean heavily on Mookie Wilson Jersey the RB duo of and . On "D," and alone should help keep the ball in his hands and pave the way to victory.Pick: Colts 27, Jaguars 17Check out CBSSports.comon this game and the rest of Week 1.